one site binding program prism 4.0 Search Results


peaq itc analysis software  (Malvern Panalytical)
99
Malvern Panalytical peaq itc analysis software
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
Peaq Itc Analysis Software, supplied by Malvern Panalytical, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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peaq itc analysis software - by Bioz Stars, 2026-03
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one-site fit log ic50 model  (GraphPad Software Inc)
90
GraphPad Software Inc one-site fit log ic50 model
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
One Site Fit Log Ic50 Model, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/one-site fit log ic50 model/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
one-site fit log ic50 model - by Bioz Stars, 2026-03
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one site binding model  (OriginLab corp)
90
OriginLab corp one site binding model
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
One Site Binding Model, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/one site binding model/product/OriginLab corp
Average 90 stars, based on 1 article reviews
one site binding model - by Bioz Stars, 2026-03
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graphpad prism-4 software  (GraphPad Software Inc)
90
GraphPad Software Inc graphpad prism-4 software
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
Graphpad Prism 4 Software, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/graphpad prism-4 software/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
graphpad prism-4 software - by Bioz Stars, 2026-03
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origin version 7.0  (OriginLab corp)
90
OriginLab corp origin version 7.0
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
Origin Version 7.0, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/origin version 7.0/product/OriginLab corp
Average 90 stars, based on 1 article reviews
origin version 7.0 - by Bioz Stars, 2026-03
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one-site binding equation graphpad prism  (GraphPad Software Inc)
90
GraphPad Software Inc one-site binding equation graphpad prism
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
One Site Binding Equation Graphpad Prism, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/one-site binding equation graphpad prism/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
one-site binding equation graphpad prism - by Bioz Stars, 2026-03
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one site-specific binding fit  (GraphPad Software Inc)
90
GraphPad Software Inc one site-specific binding fit
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
One Site Specific Binding Fit, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
one site-specific binding fit - by Bioz Stars, 2026-03
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txa2 mimetics  (Mimetics)
90
Mimetics txa2 mimetics
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
Txa2 Mimetics, supplied by Mimetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
txa2 mimetics - by Bioz Stars, 2026-03
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prism 6.0 software  (GraphPad Software Inc)
90
GraphPad Software Inc prism 6.0 software
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
Prism 6.0 Software, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prism 6.0 software/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
prism 6.0 software - by Bioz Stars, 2026-03
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prism software  (GraphPad Software Inc)
90
GraphPad Software Inc prism software
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
Prism Software, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prism software/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
prism software - by Bioz Stars, 2026-03
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graphpad prism 9  (GraphPad Software Inc)
90
GraphPad Software Inc graphpad prism 9
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
Graphpad Prism 9, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/graphpad prism 9/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
graphpad prism 9 - by Bioz Stars, 2026-03
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one site - specific binding model  (GraphPad Software Inc)
90
GraphPad Software Inc one site - specific binding model
FDA approved drugs CPZ and PCZ can bind to pG4-1. <t>Isothermal</t> <t>titration</t> <t>calorimetry</t> <t>(ITC)</t> profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .
One Site Specific Binding Model, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/one site - specific binding model/product/GraphPad Software Inc
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Image Search Results


FDA approved drugs CPZ and PCZ can bind to pG4-1. Isothermal titration calorimetry (ITC) profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .

Journal: Frontiers in Molecular Biosciences

Article Title: G4-binding drugs, chlorpromazine and prochlorperazine, repurposed against COVID-19 infection in hamsters

doi: 10.3389/fmolb.2023.1133123

Figure Lengend Snippet: FDA approved drugs CPZ and PCZ can bind to pG4-1. Isothermal titration calorimetry (ITC) profiles for the titration of CPZ (A) or PCZ (B) with ORF1 pG4-1. The upper panels show sequential injection of the ligands into ORF1 pG4-1; fitted data of integrated heat values after correction for heat of dilution plotted against molar ratio shown in lower panels; dissociation constants mentioned in the lower panel. CD spectra of ORF1 pG4-1 with increasing concentration of CPZ (C) or PCZ (D) . Fluorescence spectra of 1 μM of NMM in presence of 1 μM of ORF1 pG4-1 with increasing molar ratio of CPZ (E) or PCZ (F) .

Article Snippet: For CPZ, the integrated heat data were fit with one binding site model using the Microcal PEAQ ITC analysis software.

Techniques: Isothermal Titration Calorimetry, Titration, Injection, Circular Dichroism, Concentration Assay, Fluorescence